News from our division
Supervisor of the year award for Saskia Suijkerbuijk
Congratulations Saskia on being awarded the PhD supervisor of the year award by the PhD Council of the Graduate School of Life Sciences!
Intermediate filaments and organismal dysfunctions
Our collaborative manuscript with Florian Geisler and the group of Rudolph Leube has just been published in eLife. Congratulations all! Read the paper here.
ENW-M grant awarded
Saskia Suijkerbuijk received an Open Competition grant from the Dutch Research Council to investigate how cellular fitness is communicated in intestinal organoids.
Opening Stem cell & Organoid lab
Agathe Chaigne and Saskia Suijkerbuijk officially opened our brand new "Stem cells and Organoid" room! We are looking forward to loads of awesome experiments and happy culturing.
New additions to the team
A very special welcome to our newest team additions: the mexican salamanders Axl and Lotte!
MSCA Doctoral Network awarded
Exciting news: a Marie Curie Doctoral Network grant was awarded for the project SurfEx - Epithelial Exchange Surfaces: From organizing principles to ex vivo disease models of the gatekeepers of the body.
New labmembers
Five new members have joined our groups since the last website update! Welcome to Christian, Joren, Mohamed, Stefanos and Gwen.
Improved degron for auxin-mediated protein degradation in C. elegans
In a collaborative effort with the Boxem, Ward, and Ruijtenberg labs, Jorian Sepers shows that the mIAA7 degron greatly improves auxin-mediated protein degradation in C. elegans. Plasmids to generate CRISPR repair templates are available from Addgene.
Read the paper here
Two ENW-M grants awarded
Suzan Ruijtenberg and Mike Boxem both received an Open Competition grant from the Dutch Research Council for the single molecule visualization of translation dynamics and to investigate how epithelial cells organize themselves along an internal molecular compass. Congratulations both!
MES-3 is C. elegans SUZ12
Sensitive similarity searches and structure prediction unearthed that MES-3 is a highly divergent ortholog of the canonical PRC2 component SUZ12.
Read the paper here
New Suijkerbuijk lab member
A warm welcome to Merel van Luyk as a new PhD student in the Suijkerbuijk group! We are happy you joined and wish you great success in your PhD.
C. elegans Crumbs complex composition
Congratulations to Victoria Garcia on her paper describing the composition of the C. elegans Crumbs complex!
Read the paper here
Redundant control of lumen morphogenesis in C. elegans
Congratulations Jorian on the first paper in 2022! We show that ERM-1 phosphorylation and binding to NRFL-1 NHERF1/EBP50 redundantly control intestinal morphology.
Read the paper here