Developmental Biology

Welcome to Developmental Biology

We are home to four research groups that share a mission to decipher biological principles in the context of animal development and tissue homeostasis. We also aim to train the next generation of developmental biologists through inspiring teaching at the level of bachelor, master, and PhD education in the biology department and Utrecht Life Sciences community. Learn more about our research or teaching through the links in the menu, or continue scrolling to read the latest news from our division.

News from our division

nrfl-1 paper image

Redundant control of lumen morphogenesis in C. elegans

Congratulations Jorian on the first paper in 2022! We show that ERM-1 phosphorylation and binding to NRFL-1 NHERF1/EBP50 redundantly control intestinal morphology.

Read the paper here

new PhD students
new lab members

New colleagues

In the final months of 2021, we welcomed two new PhD students to our devision. Loes started in the Ruijtenberg group, and Olga started in the Boxem group. We are happy you joined and wish both of you great success in your PhD!

let-413 paper image

LET-413 Scribble is essential in larval epithelia

Amalia's recent publication in PLOS Genetics shows that LET-413 Scribble is essential in the epidermis for animal development, and for directed outgrowth of the seam cells. Congratulations Amalia!

Read the paper here

CeLINC paper image

Fluorescence-based protein–protein interaction assay

Jason's paper in Genetics presents C. elegans light-induced coclustering (CeLINC), an optical binary protein–protein interaction assay to determine whether two proteins interact in vivo.

Read the paper here

Inge with her best course award

Best Biology course award

Inge The received the 'best Biology level 2 course of the year' award for her work developing and coordinating the Developmental Biology course in 2019/2020. Congratulations Inge and all teachers involved!

BBLN-1 mutant

Publication in Current Biology

Our new article shows that the novel and evolutionary conserved protein BBLN-1 (bublin) is essential for intermediate filament organization and lumen morphology in the C. elegans gut.

Read the paper here