Universiteit Utrecht Faculteit Farmacie


Farmaceutische Analyse

Zuurgetal


Bepaling van het zuurgetal

2.5.1. ACID VALUE

The acid value IA is the number that expresses in milligrams the quantity of potassium hydroxide required to neutralise the free acids present in 1 g of the substance.

Dissolve 10.00 g of the substance to be examined, or the quantity prescribed (m g) in 50 ml of a mixture of equal volumes of alcohol R and ether R, previously neutralised with 0.1 M potassium hydroxide, unless otherwise specified, using 0.5 ml of phenolphthalein solution R1 as indicator. When the substance to be examined has dissolved, titrate with 0.1 M potassium hydroxide until the pink colour persists for at least 15 s (n ml of 0.1 M potassium hydroxide).

IA= 5.160 . n / m


Farmaceutische Analyse 5e-jaar |

10 september 1999