Specific optical rotation (2.2.7). Dissolve 5.00 g of the substance to be examined and 6.4 g of disodium tetraborate R in 40 ml of water R. Allow to stand for 1 h, shaking occasionally, and dilute to 50.0 ml with water R. Filter if necessary. The specific optical rotation is + 4.0� to + 7.0�, calculated with reference to the anhydrous substance.Sorbitol
Specific optical rotation (2.2.7). Dissolve 2.00 g of the substance to be examined and 2.6 g of disodium tetraborate R in about 20 ml of water R previously heated to 30 �C; shake continuously for 15 min to 30 min without further heating. Dilute the resulting clear solution to 25.0 ml with water R. The specific optical rotation is + 23� to + 25�, calculated with reference to the dried substance.
2 juli 1999