Identification
B. To 5 ml of solution S add 0.1 ml of phenolphthalein solution R. The solution is red. On the addition of 5 ml of glycerol (85 per cent) R the colour disappears.
Assay
Dissolve 20 g of mannitol R in 100 ml of water R, heating if necessary, cool, add 0.5 ml of phenolphthalein solution R and neutralise with 0.1 M sodium hydroxide until a pink colour is obtained. To this solution add 3.00 g of the substance to be examined. Heat until dissolution is complete, cool, and titrate with 1 M sodium hydroxide until the pink colour reappears.
2 juli 1999